The Role of Monoclonal Antibodies in the Treatment of Atherosclerosis

Curr Probl Cardiol. 2023 Apr;48(4):101585. doi: 10.1016/j.cpcardiol.2023.101585. Epub 2023 Jan 7.

Abstract

Atherosclerosis is an inflammatory disease that involves antibody immune responses. Progression of hyperlipidemia can lead to atherosclerosis and subsequently cardiovascular diseases with high mortality. Additional lipid-lowering therapies other than statins are currently being studied, such as monoclonal antibodies. In this contemporary review, we examine the various monoclonal antibody therapies targeted toward atherosclerotic disease.

Publication types

  • Review

MeSH terms

  • Antibodies, Monoclonal
  • Atherosclerosis*
  • Cardiovascular Diseases*
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors*

Substances

  • Antibodies, Monoclonal
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors