Characterization of the novel HLA-C*08:258 and -C*12:374 alleles by two different sequencing-based typing techniques

HLA. 2023 Jun;101(6):690-691. doi: 10.1111/tan.14963. Epub 2023 Jan 13.

Abstract

The novel HLA-C*08:258 and -C*12:374 alleles differ from HLA-C*08:02:01:01 and -C*12:03:01:01 by one nucleotide substitution.

Keywords: HLA-C; NGS; nanotype sequencing; sequencing-based typing.

MeSH terms

  • Alleles
  • Genes, MHC Class I
  • HLA-C Antigens* / genetics
  • High-Throughput Nucleotide Sequencing* / methods
  • Histocompatibility Testing / methods
  • Humans
  • Sequence Analysis, DNA / methods

Substances

  • HLA-C Antigens