Development of magnetic dispersive micro-solid phase extraction of four phenolic compounds from food samples based on magnetic chitosan nanoparticles and a deep eutectic supramolecular solvent

Xiaoping Hai; Feng Shi; Yun Zhu; Lei Ma; Lina Wang; Jinfang Yin; Xiaofen Li; Zhi Yang; Mingwei Yuan; Huabin Xiong; Yuntao Gao

doi:10.1016/j.foodchem.2022.135338

Development of magnetic dispersive micro-solid phase extraction of four phenolic compounds from food samples based on magnetic chitosan nanoparticles and a deep eutectic supramolecular solvent

Food Chem. 2023 Jun 1:410:135338. doi: 10.1016/j.foodchem.2022.135338. Epub 2022 Dec 27.

Authors

Xiaoping Hai¹, Feng Shi¹, Yun Zhu¹, Lei Ma¹, Lina Wang¹, Jinfang Yin¹, Xiaofen Li¹, Zhi Yang¹, Mingwei Yuan², Huabin Xiong³, Yuntao Gao⁴

Affiliations

¹ School of Chemistry and Environment, Yunnan Minzu University, Kunming 650500, PR China.
² National and Local Joint Engineering Research Center for Green Preparation Technology of Biobased Materials, Yunnan Minzu University, Kunming 650500, PR China.
³ School of Chemistry and Environment, Yunnan Minzu University, Kunming 650500, PR China. Electronic address: xionghuabin@ynni.edu.cn.
⁴ National and Local Joint Engineering Research Center for Green Preparation Technology of Biobased Materials, Yunnan Minzu University, Kunming 650500, PR China. Electronic address: 040343@ymu.edu.cn.

PMID: 36621335
DOI: 10.1016/j.foodchem.2022.135338

Abstract

A magnetic dispersive micro-solid phase extraction technique (CS@Fe₃O₄-MD-μSPE-DESP) based on magnetic chitosan nanoparticles and a deep eutectic supramolecular solvent was developed and applied to determinations of four phenolic compounds in food samples. To prevent environmental pollution and the introduction of toxic substances, deep eutectic supramolecular solvents (DESPs), which exhibited greater desorption capacities than conventional organic solvents and deep eutectic solvents, were used as novel green eluents for the first time. Some important parameters were screened by the Plackett-Burman method and then further optimized with response surface methodology (RSM). Under the optimal conditions, the proposed method showed excellent methodological indices with linearity over the range 0.1-200.0 µg·mL^-1, R² > 0.9988, extraction recoveries above 94.8 %, and precision (RSD%) below 2.9 %. The established method finishes the process of adsorption and desorption in approximately 3 min and enhances the efficiency for determination of phenolic compounds.

Keywords: Deep eutectic supramolecular solvent; High-performance liquid chromatography; Magnetic chitosan nanoparticle; Phenolic compounds; Response surface methodology.

MeSH terms

Chitosan*
Liquid Phase Microextraction* / methods
Magnetic Phenomena
Magnetics
Solid Phase Extraction / methods
Solvents

Substances

Solvents
Chitosan