Health Effects of Exposure to Indoor Semi-Volatile Organic Compounds in Chinese Building Environment: A Systematic Review

Int J Environ Res Public Health. 2022 Dec 30;20(1):678. doi: 10.3390/ijerph20010678.

Abstract

People spend a considerable portion of their lives indoors; thus, the quality of the indoor environment is crucial. Semi-volatile organic compounds (SVOCs) are among the primary indoor pollutants responsible for various health risks. This paper systematically reviews the impact of SVOC exposure on human health in Chinese built environments. Based on a set of criteria, we judged 12 publications as providing sufficient information on both SVOC exposure and health effects to inform the relationship. Out of six studies on polycyclic aromatic hydrocarbons (PAHs), three observed a positive association between PAH exposure and lung cancer. Out of six studies of phthalate exposure, two studies reported a significant positive association between DEP and DiBP and asthma, between DEP and DEHP and dry cough among children, and between DBP and rhinitis among younger adults. The results of this review suggest that there might be a link between phthalate exposure and asthma and allergies, as well as a link between PAH exposure and lung cancer. However, due to the limited number of studies conducted, more evidence is necessary to definitively guide the establishment of standards for SVOC control in China.

Keywords: China; building environment; health effects; phthalate esters (PAEs); polycyclic aromatic (PAHs); semi-volatile organic compounds (SVOCs).

Publication types

  • Systematic Review
  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Air Pollutants* / analysis
  • Air Pollutants* / toxicity
  • Air Pollution, Indoor* / adverse effects
  • Air Pollution, Indoor* / analysis
  • Asthma* / chemically induced
  • Asthma* / epidemiology
  • Child
  • China
  • Environmental Exposure / adverse effects
  • Environmental Exposure / analysis
  • Humans
  • Lung Neoplasms*
  • Phthalic Acids* / analysis
  • Polycyclic Aromatic Hydrocarbons* / analysis
  • Polycyclic Aromatic Hydrocarbons* / toxicity
  • Volatile Organic Compounds* / analysis
  • Volatile Organic Compounds* / toxicity

Substances

  • Air Pollutants
  • phthalic acid
  • Phthalic Acids
  • Polycyclic Aromatic Hydrocarbons
  • Volatile Organic Compounds

Grants and funding

This research was funded by the National Key Research and Development Program of China (2017YFC0702700), the National Natural Science Foundation of China (21207097), and the Natural Science Foundation of Tianjin City (21JCZDJC00540).