Dental trauma in children and adolescents with attention-deficit/hyperactivity disorder: A systematic review and meta-analysis

Spec Care Dentist. 2023 Sep-Oct;43(5):635-644. doi: 10.1111/scd.12819. Epub 2023 Jan 5.

Abstract

Aim: Attention-deficit/hyperactivity disorder (ADHD) is a childhood neurodevelopmental disorder primarily characterized by inattention and hyperactivity that affects approximately 7.2% of children and adolescents worldwide. This study aimed to assess whether children and adolescents with ADHD were more likely to have dental trauma when compared to their healthy peers.

Methods: This study was reported following the statements proposed in MOOSE (Meta-analyses Of Observational Studies in Epidemiology). PubMed, Web of Science, Scopus, Embase, APA PsycINFO, LILACS, and grey literature were searched until October 2022. Observational studies with a control group were eligible. The risk of bias was assessed using the Newcastle-Ottawa Scale. The meta-analysis was performed using the R language. GRADE (Grading of Recommendations Assessment, Development and Evaluation) was applied.

Results: A total of 239 studies were detected; of these, six were included in the qualitative synthesis and four were merged in the meta-analysis (OR = 1.80 [1.16-2.80]; I2 = 18.6% [0.0%-87.5%]). The risk of bias was high. The strength of the evidence was "very low."

Conclusion: Children and adolescents with ADHD are more likely to have dental trauma than their non-ADHD peers. However, due to limitations in the design of the included studies, a causal relationship cannot be established.

Keywords: attention deficit hyperactivity disorder; dental trauma; meta-analysis; neurodevelopmental disorders; oral health; traumatic dental injuries.

Publication types

  • Meta-Analysis
  • Systematic Review
  • Review

MeSH terms

  • Adolescent
  • Attention Deficit Disorder with Hyperactivity* / epidemiology
  • Child
  • Humans
  • Observational Studies as Topic