High-dose insulin should NOT be used without vasopressors in calcium channel blocker toxicity

Br J Clin Pharmacol. 2023 Apr;89(4):1275-1278. doi: 10.1111/bcp.15642. Epub 2023 Jan 5.

Authors

Saskia J Rietjens¹, Tessa E van Riemsdijk¹, Maaike A Sikma^{1

2}, Dylan W de Lange^{1

2}

Affiliations

¹ Dutch Poisons Information Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
² Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.

PMID: 36604782
DOI: 10.1111/bcp.15642

No abstract available

Keywords: calcium channel blocker; high-dose insulin; intoxication; overdose; poisoning; vasopressors.

MeSH terms

Calcium Channel Blockers* / adverse effects
Drug Overdose* / drug therapy
Humans
Hypoglycemic Agents / adverse effects
Insulin / adverse effects
Vasoconstrictor Agents

Substances

Calcium Channel Blockers
Insulin
Hypoglycemic Agents
Vasoconstrictor Agents