C-C Coupling through Nitrogen Deletion: Application to Library Synthesis

Serhii Holovach; Kostiantyn P Melnykov; Illia Poroshyn; Rustam T Iminov; Dmytro Dudenko; Ivan Kondratov; Mark Levin; Oleksandr O Grygorenko

doi:10.1002/chem.202204025

C-C Coupling through Nitrogen Deletion: Application to Library Synthesis

Chemistry. 2023 Jan 18;29(4):e202204025. doi: 10.1002/chem.202204025. Epub 2023 Jan 4.

Authors

Serhii Holovach¹, Kostiantyn P Melnykov^{1

2}, Illia Poroshyn¹, Rustam T Iminov¹, Dmytro Dudenko^{1

3}, Ivan Kondratov^{1

4}, Mark Levin⁵, Oleksandr O Grygorenko^{1

2}

Affiliations

¹ Enamine Ltd., Chervonotkatska Street 78, Kyїv, 02094, Ukraine.
² Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyїv, 01601, Ukraine.
³ Chemspace, Chervonotkatska Street 85, Kyїv, 02094, Ukraine.
⁴ V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, Akademik Kukhar Street 1, Kyїv, 02094, Ukraine.
⁵ Department of Chemistry, University of Chicago, 5735 S Ellis Ave, Chicago, IL, 60637, USA.

PMID: 36599487
DOI: 10.1002/chem.202204025

Abstract

Invited for the cover of this issue are Oleksandr Grygorenko and his Ukrainian colleagues at Enamine Ltd., Taras Shevchenko National University of Kyiv, National Academy of Sciences of Ukraine, and ChemSpace, as well as Mark Levin at the University of Chicago. The image depicts application of a nitrogen-deleting anomeric amide to parallel C(sp³ )-C(sp³ ) coupling. Read the full text of the article at 10.1002/chem.202203470.