Sentinel lymphatic mapping for gynecologic malignancies

Curr Opin Obstet Gynecol. 2023 Feb 1;35(1):43-53. doi: 10.1097/GCO.0000000000000841.

Abstract

Purpose of review: To summarize the latest data in Gynecologic Oncology for the use of sentinel lymphatic mapping in vulvar, uterine, and cervical cancers.

Recent findings: To decrease morbidity and improve detection of lymphatic metastasis, lymphatic mapping with sentinel lymph node biopsy is emerging as standard of care over conventional systemic lymphadenectomy in the surgical management of gynecologic malignancies.

Summary: Sentinel lymph node mapping with biopsy is one of the most significant advances in cancer surgery. The presence of nodal metastasis is not only a prognostic factor for recurrence and survival in patients with gynecologic malignancies, but also guides assessment for adjuvant treatment. This review article discusses the most recent clinical updates in sentinel lymph node mapping, dissection, and management in vulvar cancer, endometrial cancer, and cervical cancer.

Publication types

  • Review

MeSH terms

  • Endometrial Neoplasms* / diagnostic imaging
  • Endometrial Neoplasms* / surgery
  • Female
  • Genital Neoplasms, Female* / diagnostic imaging
  • Genital Neoplasms, Female* / surgery
  • Humans
  • Lymph Node Excision
  • Lymph Nodes / pathology
  • Lymphatic Metastasis / pathology
  • Neoplasm Staging
  • Sentinel Lymph Node Biopsy
  • Uterine Cervical Neoplasms* / diagnosis
  • Uterine Cervical Neoplasms* / pathology
  • Uterine Cervical Neoplasms* / surgery
  • Vulvar Neoplasms* / diagnosis
  • Vulvar Neoplasms* / surgery