Influence of anti-obesity strategies on brain function in health and review: A review

Neurochem Int. 2023 Feb:163:105468. doi: 10.1016/j.neuint.2022.105468. Epub 2022 Dec 30.

Abstract

The aim of this review was to investigate in the literature the application of strategies such as low carbohydrate diet (LCD), ketogenic diet (KD) and intermittent fasting (IF) and their effects on the CNS. We performed a narrative review of the literature. The search was specifically carried out in PubMed, selecting articles in English, which had the following keywords: obesity, central nervous system, low carb diet, ketogenic diet and intermittent fasting, using the narrative review methodology. The studies found show that the benefits of the LCD, KD and IF strategies, at the CNS level, have a strong influence on the mechanisms of hunger and satiety, as well as on the reduction of food reward and show improvement in memory and mood influenced by the interventions.

Keywords: Central nervous system; Intermittent fasting; Ketogenic diet; Low carb diet; Obesity.

Publication types

  • Review

MeSH terms

  • Brain
  • Diet, Carbohydrate-Restricted
  • Diet, Ketogenic* / methods
  • Humans
  • Nervous System Physiological Phenomena*
  • Obesity / drug therapy