Dimeric alkaloids from the barks of Erythrina variegata as well as their occurrence

Yu-Ting Tang; Zhuo-Ran Si; Mei-Fen Bao; Xiang-Hai Cai

doi:10.1016/j.fitote.2022.105408

Dimeric alkaloids from the barks of Erythrina variegata as well as their occurrence

Fitoterapia. 2023 Apr:166:105408. doi: 10.1016/j.fitote.2022.105408. Epub 2022 Dec 28.

Authors

Yu-Ting Tang¹, Zhuo-Ran Si², Mei-Fen Bao¹, Xiang-Hai Cai³

Affiliations

¹ State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China.
² College of Life Sciences, Zhejiang University, Hangzhou 310058, PR China.
³ State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China. Electronic address: xhcai@mail.kib.ac.cn.

PMID: 36586624
DOI: 10.1016/j.fitote.2022.105408

Abstract

Thirteen undescribed dimeric Erythrina alkaloids, named as erythrivarines A1-A13, were isolated from the barks of Erythrina variegata L. and. Their structures were determined on the basis of NMR, UV and mass spectral analyses. Dimeric Erythrina alkaloid with a C-8/8' linkage in erythrivarine A1 was not yet reported. Representative dimers from titled plant were used to prove their occurrence as natural products by LC - MS detection. Additionally, simultaneous investigation enabled us to propose the natural property of seemingly artificial Erythrina alkaloid with acetonyl group.

Keywords: Dimers; Erythrina variegata; Erythrivarines A1–A13; Fabaceae.

MeSH terms

Alkaloids* / chemistry
Erythrina* / chemistry
Indolizines*
Mass Spectrometry
Molecular Structure
Plant Extracts / chemistry

Substances

Alkaloids
Plant Extracts
Indolizines