The Role of Endoscopic Management in Afferent Loop Syndrome

Gut Liver. 2023 May 15;17(3):351-359. doi: 10.5009/gnl220205. Epub 2022 Dec 29.

Abstract

Afferent loop syndrome (ALS) is a morbid complication that may occur after gastrectomy and gastrojejunostomy reconstruction. The aim of this article is to review the different endoscopic treatment options of ALS. We describe the evolution of the endoscopic treatment of ALS and its limitations despite the overall propitious profile. We analyze the advantages of endoscopic ultrasound-guided entero-enterostomy (EUS EE) over enteroscopy-guided intervention, and the clinical outcomes of EUS EE. We expound on pre-procedural considerations, intra-procedural techniques and post-procedural care following EUS EE. We conclude that given the simplification of the technique and the ability to place a stent away from the tumor, EUS EE is a promising technique that will likely be established as the treatment of choice for ALS.

Keywords: Afferent loop syndrome; Endoscopic ultrasonography; Enterostomy; Gastrojejunostomy; Self expandable metal stent.

Publication types

  • Review

MeSH terms

  • Afferent Loop Syndrome* / diagnostic imaging
  • Afferent Loop Syndrome* / etiology
  • Afferent Loop Syndrome* / surgery
  • Endoscopy
  • Endosonography / methods
  • Humans
  • Stents
  • Ultrasonography, Interventional