Preparation of temperature-responsive nanomicelles with AIE property as fluorescence probe for detection of Fe3+ and Fe2

Xinhui Hou; Yifan Song; Yupeng Lv; Peiyao Wang; Kun Chen; Guiying Li; Lei Guo

doi:10.1016/j.saa.2022.122254

Preparation of temperature-responsive nanomicelles with AIE property as fluorescence probe for detection of Fe³⁺ and Fe²

Spectrochim Acta A Mol Biomol Spectrosc. 2023 Apr 5:290:122254. doi: 10.1016/j.saa.2022.122254. Epub 2022 Dec 24.

Authors

Xinhui Hou¹, Yifan Song², Yupeng Lv¹, Peiyao Wang¹, Kun Chen¹, Guiying Li³, Lei Guo⁴

Affiliations

¹ School of Chemistry and Materials Science, Ludong University, Yantai 264025, China.
² Chu Kochen Honors College, Zhejiang University, Hangzhou 310058, China.
³ School of Chemistry and Materials Science, Ludong University, Yantai 264025, China. Electronic address: guiyingli@126.com.
⁴ School of Chemistry and Materials Science, Ludong University, Yantai 264025, China. Electronic address: unikguo@gmail.com.

PMID: 36577245
DOI: 10.1016/j.saa.2022.122254

Abstract

Temperature-responsive nanomicelles with aggregation induced emission (AIE) property were prepared by the host-guest complexation of ferrocene functionalized tetraphenyl (TPE-Fc) and β-cyclodextrin-poly (N-isopropylacrylamide) (β-CD-(PNIPAM)₇). The AIE chromophore TPE-Fc bound to the hydrophobic cavity of cyclodextrin serves as the core of micelles, and temperature sensitive PNIPAM serves as the shell to give the micelles good solubility. The size of the nanomicelles is about 100 nm. At the excitation wavelength of 340 nm, the strongest fluorescent emission peak was 421 nm. The introduction of cyclodextrin star polymer increased the fluorescence intensity of nanomicelles, thus improving the recognition of probe to Fe³⁺ and Fe²⁺. The fluorescent probe can quickly detect Fe³⁺ and Fe²⁺ in water within 5 min even in the presence of various interfering ions. The detection limits of Fe³⁺ and Fe²⁺ were 1.04 μM and 0.78 μM, respectively in the range of 10-90 μM. The formation of complex between the probe and Fe³⁺/Fe²⁺ was supported by Job's plot. The probe was successfully applied to the detection of Fe³⁺and Fe²⁺ in actual water sample with a good recovery. In addition, a possible sensing mechanism for the interaction of iron ions with amide bond groups of nanomicelles was proposed.

Keywords: Aggregation induced emission; Detection; Fe (II) ion; Fe (III) ion; Fluorescence probe.