Hypotony in uveitis: an overview of medical and surgical management

Br J Ophthalmol. 2023 Nov 22;107(12):1765-1770. doi: 10.1136/bjo-2022-322814.

Abstract

Hypotony is a well-recognised, sight-threatening complication of uveitis. It can also be the final common endpoint for a multitude of disease entities. Multiple mechanisms underlie hypotony, and meticulous clinical history alongside ocular phenotyping is necessary for choosing the best intervention and therapeutic management. In this narrative review, a comprehensive overview of medical and surgical treatment options for the management of non-surgically induced hypotony is provided. Management of ocular hypotony relies on the knowledge of the aetiology and mechanisms involved. An understanding of disease trajectory is vital to properly educate patients. Both anatomical and functional outcomes depend on the underlying pathophysiology and choice of treatment.

Keywords: Ciliary body; Inflammation; Intraocular pressure.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ciliary Body / surgery
  • Humans
  • Intraocular Pressure
  • Ocular Hypotension* / diagnosis
  • Ocular Hypotension* / etiology
  • Retrospective Studies
  • Uveitis* / diagnosis
  • Uveitis* / drug therapy
  • Uveitis* / surgery