The radial artery pulse wave contains a wealth of physiological and pathological information about the human body, and non-invasive studies of the radial artery pulse wave can assess arterial vascular elasticity in different age groups.The piezoelectric pulse wave transducers were used to non-invasively acquire radial artery pulse waves at different contact pressures in young and middle-aged and elderly populations. The radial artery waveforms were decomposed using a triangular blood flow model fitting method to obtain forward and reflected waves and calculate reflection parameters. Finally a correlation analysis and regression analysis of the contact pressure Psensor with the reflection parameters was carried out. The results showed that the reflection parameters RM, RI and Rd had a strong negative correlation with Psensor in both types of subjects, and the correlation coefficients and slopes of the regression curves were significantly different between the two types of subjects (P<0.05). Based on the results of this study, excessive contact pressure on the transducer should be avoided when detecting radial artery reflection waves in clinical practice. The results also show that the magnitude of the slope of the regression curve between the reflection parameters and the transducer contact pressure may be a potentially useful indicator for quantifying the elastic properties of the vessel.
桡动脉脉搏波蕴含了人体丰富的生理、病理信息，对桡动脉脉搏波的无创研究可以评估不同年龄段人群的动脉血管弹性。实验利用压电式脉搏波传感器无创采集年轻人群体和中老年人群体在不同接触压力下的桡动脉脉搏波，并使用三角形血流模型拟合法分解桡动脉波形，得到前向波与反射波并计算反射参数，最后对接触压力Psensor与反射参数进行相关性分析和回归分析。结果表明，两类受试者中反射参数RM、RI、Rd 均与Psensor具有较强的负相关性，且两类受试者的相关系数及回归曲线斜率有显著差异（P<0.05）。基于此研究结果，临床上检测桡动脉反射波时，应当避免对传感器施加过大的接触压力；同时表明，反射参数与传感器接触压力的回归曲线斜率大小也可能是量化血管弹性的一个潜在有效指标。.
Keywords: Correlation analysis; Radial artery; Regression analysis; Wave reflection; Waveform decomposition.