Editorial: The mechanism and novel strategies of overcoming resistance of hematological malignancies to CAR-T cell killing

Front Immunol. 2022 Dec 9:13:1093339. doi: 10.3389/fimmu.2022.1093339. eCollection 2022.

Tingting Zhang^{1

2

3}, Tiantian Yu⁴, Xingcheng Yang^{5

6}, Weiwei Tian^{2

3}, Jia Wei^{2

3

5

6}

¹ Cancer center, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
² Department of Hematology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
³ Sino-German Joint Oncological Research Laboratory, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, Shanxi, China.
⁴ Division of Hematopathology, Duke University Medical Center and Duke Cancer Institute, Durham, NC, United States.
⁵ Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
⁶ Immunotherapy Research Center for Hematologic Diseases of Hubei Province, Wuhan, Hubei, China.

No abstract available

Keywords: CAR-T; hematological malignancies; mechanism; novel strategies; overcome resistance.

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