Diagnosis and Management of Supine and Nocturnal Hypertension in Orthostatic Hypotension: A Review

Curr Hypertens Rev. 2023;19(1):19-26. doi: 10.2174/1573402119666221222160649.

Abstract

The prevalence of supine and nocturnal hypertension (S-N-HT) is high among patients with orthostatic hypotension (OH), especially in those who have a neurogenic aetiology. The evidence suggests that S-N-HT exacerbates OH, although it is unclear whether pharmacologic treatment of S-N-HT will improve OH. S-N-HT has also been associated with target organ damage. Therefore, assessment and management of S-N-HT should be an integral part of managing OH, but it is often overlooked in clinical practice.

Keywords: Supine hypertension; ambulatory blood pressure; autonomic dysfunction; circadian blood pressure rhyth; nocturnal hypertension; orthostatic hypotension.

Publication types

  • Review

MeSH terms

  • Humans
  • Hypertension* / diagnosis
  • Hypertension* / drug therapy
  • Hypertension* / epidemiology
  • Hypotension, Orthostatic* / diagnosis
  • Hypotension, Orthostatic* / epidemiology
  • Hypotension, Orthostatic* / therapy
  • Supine Position