The outcomes of COVID-19 pneumonia in children-clinical, radiographic, and pulmonary function assessment

Pediatr Pulmonol. 2023 Apr;58(4):1042-1050. doi: 10.1002/ppul.26291. Epub 2023 Jan 4.

Abstract

Objectives: The goal of this study was to assess the pulmonary sequelae of COVID-19 pneumonia in children.

Study design: Children (0-18 years old) diagnosed with COVID-19 pneumonia hospitalized between March 2020 and March 2021 were included in this observational study. All children underwent follow-up visits 3 months postdischarge, and if any abnormalities were stated, a second visit after the next 3 months was scheduled. Clinical assessment included medical history, physical examination, lung ultrasound (LUS) using a standardized protocol, and pulmonary function tests (PFTs). PFTs results were compared with healthy children.

Results: Forty-one patients with COVID-19 pneumonia (severe disease n = 3, mechanical ventilation, n = 0) were included in the study. Persistent symptoms were reported by seven (17.1%) children, the most common was decreased exercise tolerance (57.1%), dyspnea (42.9%), and cough (42.9%). The most prevalent abnormalities in LUS were coalescent B-lines (37%) and small subpleural consolidations (29%). The extent of LUS abnormalities was significantly greater at the first than at the second follow-up visit (p = 0.03). There were no significant differences in PFTs results neither between the study group and healthy children nor between the two follow-up visits in the study group.

Conclusions: Our study shows that children might experience long-term sequelae following COVID-19 pneumonia. In the majority of cases, these are mild and resolve over time.

Keywords: SARS-CoV-2; complications; long COVID; lungs ultrasound; pediatric; pulmonary function tests; sequelae; viral pneumonia.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Aftercare
  • COVID-19* / complications
  • Child
  • Child, Preschool
  • Humans
  • Infant
  • Infant, Newborn
  • Lung / diagnostic imaging
  • Patient Discharge
  • SARS-CoV-2
  • Ultrasonography / methods