Heparin desensitisation prior to cardiopulmonary bypass in a patient with alpha-gal allergy

Abstract

This case report describes the implementation of a heparin desensitisation strategy for a patient with confirmed galactose-alpha-1,3-galactose (alpha-gal) allergy, prior to cardiac surgery. We describe the pre-, intra- and postoperative management. We believe this report can enhance the limited data currently in existence on alternative strategies for heparin utilisation in cardiopulmonary bypass in a previously intolerant patient population.

Keywords: cardiopulmonary bypass; desensitisation; heparin.