This paper proposes a deep learning method for phase retrieval from two interferograms. The proposed method converts phase retrieval into the Zernike coefficient extraction problem, which can achieve Zernike coefficient extraction from two interferograms with random phase shifts. After knowing Zernike coefficients, the phase distribution can be retrieved using Zernike polynomials. The pre-filtering and phase unwrapping process are not required using the proposed method. The simulated data are analyzed, and the root mean square (RMS) of phase error reaches 0.01 λ. The effectiveness of the method is verified by the measured data.