mTOR Signaling Network in Cell Biology and Human Disease

Int J Mol Sci. 2022 Dec 18;23(24):16142. doi: 10.3390/ijms232416142.

Abstract

The mechanistic target of rapamycin (mTOR) is a serine/threonine protein kinase that regulates multiple processes, including gene transcription, protein synthesis, ribosome biogenesis, autophagy, cell metabolism, and cell growth [...].

Publication types

  • Editorial

MeSH terms

  • Autophagy
  • Humans
  • Mechanistic Target of Rapamycin Complex 1 / metabolism
  • Protein Biosynthesis
  • Signal Transduction* / genetics
  • TOR Serine-Threonine Kinases* / metabolism

Substances

  • Mechanistic Target of Rapamycin Complex 1
  • TOR Serine-Threonine Kinases
  • MTOR protein, human