Blood glucose stability in diabetic patients determines the degree of health, and changes in blood glucose levels are related to the outcome of diabetic patients. Therefore, accurate monitoring of blood glucose has a crucial role in controlling diabetes. Aiming at the problem of high volatility of blood glucose concentration in diabetic patients and the limitations of a single regression prediction model, this paper proposes a method for predicting blood glucose values based on particle swarm optimization and model fusion. First, the Kalman filtering algorithm is used to smooth and reduce the noise of the sensor current signal to reduce the effect of noise on the data. Then, the hyperparameter optimization of Extreme Gradient Boosting (XGBoost) and Light Gradient Boosting Machine (LightGBM) models is performed using particle swarm optimization algorithm. Finally, the XGBoost and LightGBM models are used as the base learner and the Bayesian regression model as the meta-learner, and the stacking model fusion method is used to achieve the prediction of blood glucose values. In order to prove the effectiveness and superiority of the method in this paper, we compared the prediction results of stacking fusion model with other 6 models. The experimental results show that the stacking fusion model proposed in this paper can accurately predict blood glucose values, and the average absolute percentage error of blood glucose prediction is 13.01%, and the prediction error of the stacking fusion model is much lower than that of the other six models. Therefore, the proposed diabetes blood glucose prediction method in this paper has superiority.
Keywords: blood glucose; diabetes mellitus; model fusion; particle swarm optimization.