Progress of Enzymatic and Non-Enzymatic Electrochemical Glucose Biosensor Based on Nanomaterial-Modified Electrode

Biosensors (Basel). 2022 Dec 6;12(12):1136. doi: 10.3390/bios12121136.

Abstract

This review covers the progress of nanomaterial-modified electrodes for enzymatic and non-enzymatic glucose biosensors. Fundamental insights into glucose biosensor components and the crucial factors controlling the electrochemical performance of glucose biosensors are discussed in detail. The metal, metal oxide, and hybrid/composite nanomaterial fabrication strategies for the modification of electrodes, mechanism of detection, and significance of the nanomaterials toward the electrochemical performance of enzymatic and non-enzymatic glucose biosensors are compared and comprehensively reviewed. This review aims to provide readers with an overview and underlying concept of producing a reliable, stable, cost-effective, and excellent electrochemical performance of a glucose biosensor.

Keywords: electrochemical sensor; enzyme immobilization; glucose detection; glucose oxidation; metal and metal oxide nanomaterials.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques*
  • Electrochemical Techniques
  • Electrodes
  • Glucose
  • Nanostructures*

Substances

  • Glucose