Effects of Electrical Pulse Width and Output Irradiance on Intense Pulse Light Inactivation

Bioengineering (Basel). 2022 Nov 26;9(12):730. doi: 10.3390/bioengineering9120730.

Abstract

The effects of electrical pulse width and output irradiance on the inactivation effect of intense pulse light (IPL) are studied in this paper. The measured radiant efficiency of pulsed xenon lamp can be more than 50%, and its irradiance can reach levels 100-times greater than that of a low-pressure mercury lamp. Staphylococcus aureus is used in inactivation experiments. When the irradiance and dose are both constant, there is no significant difference in inactivation efficiency when the pulse width is changed. However, a narrow pulse width corresponding to high irradiance at the same single-pulsed dose displays better inactivation effect. Experimental results are compared between the xenon lamp and low-pressure mercury lamp. The reduction factor (RF) value of the xenon lamp is more than 1.0 higher under the condition of both the same dose and irradiance. In order to achieve the same RF value, the dose of continuous-wave light must be at least three-times greater than that of pulsed light. The spectral action of the pulsed light is also studied. It is confirmed that UVC plays a major role across the whole spectrum. The experimental results show that extreme high-pulsed irradiance presents the main contributing factor behind the excellent bactericidal effect of IPL.

Keywords: inactivation efficiency; intense pulse light (IPL); irradiance; pulse width; spectral action.