A balanced measure shows superior performance of pseudobulk methods in single-cell RNA-sequencing analysis
Nat Commun
.
2022 Dec 22;13(1):7851.
doi: 10.1038/s41467-022-35519-4.
Authors
Alan E Murphy
1
2
,
Nathan G Skene
3
4
Affiliations
1
UK Dementia Research Institute at Imperial College London, London, W12 0BZ, UK. a.murphy@imperial.ac.uk.
2
Department of Brain Sciences, Imperial College London, London, W12 0BZ, UK. a.murphy@imperial.ac.uk.
3
UK Dementia Research Institute at Imperial College London, London, W12 0BZ, UK. n.skene@imperial.ac.uk.
4
Department of Brain Sciences, Imperial College London, London, W12 0BZ, UK. n.skene@imperial.ac.uk.
PMID:
36550119
PMCID:
PMC9780232
DOI:
10.1038/s41467-022-35519-4
No abstract available
Publication types
Letter
Research Support, Non-U.S. Gov't
Comment
MeSH terms
High-Throughput Nucleotide Sequencing* / methods
RNA / genetics
Sequence Analysis, RNA / methods
Single-Cell Analysis / methods
Software*
Substances
RNA
Grants and funding
MR/T04327X/1/MRC_/Medical Research Council/United Kingdom