OrganelX web server for sub-peroxisomal and sub-mitochondrial protein localization and peroxisomal target signal detection

Marco Anteghini; Asmaa Haja; Vitor A P Martins Dos Santos; Lambert Schomaker; Edoardo Saccenti

doi:10.1016/j.csbj.2022.11.058

OrganelX web server for sub-peroxisomal and sub-mitochondrial protein localization and peroxisomal target signal detection

Comput Struct Biotechnol J. 2022 Dec 5:21:128-133. doi: 10.1016/j.csbj.2022.11.058. eCollection 2023.

Authors

Marco Anteghini^{1

2}, Asmaa Haja³, Vitor A P Martins Dos Santos^{2

4}, Lambert Schomaker³, Edoardo Saccenti¹

Affiliations

¹ Laboratory of Systems and Synthetic Biology, Wageningen University & Research, Wageningen, The Netherlands.
² LifeGlimmer GmbH, Berlin, Germany.
³ Bernoulli Institute, University of Groningen, Groningen, The Netherlands.
⁴ Bioprocess Engineering, Wageningen University & Research, Wageningen, The Netherlands.

Abstract

We present the OrganelX e-Science Web Server that provides a user-friendly implementation of the In-Pero and In-Mito classifiers for sub-peroxisomal and sub-mitochondrial localization of peroxisomal and mitochondrial proteins and the Is-PTS1 algorithm for detecting and validating potential peroxisomal proteins carrying a PTS1 signal sequence. The OrganelX e-Science Web Server is available at https://organelx.hpc.rug.nl/fasta/.

Keywords: Peroxisomal-targeting-signal; Peroxisome; Sub-cellular localization; Sub-mithocondrial localization; Sub-peroxisomal localization.