Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles

RSC Adv. 2022 Dec 12;12(54):35484-35493. doi: 10.1039/d2ra06306a. eCollection 2022 Dec 6.

Abstract

Hetero-nanoparticles self-assembled from a conjugate bearing folic acid as the targeting agent, and another bearing paclitaxel as the active agent are reported. Hetero-nanoparticles containing varying percentages of folic acid conjugates are characterised, and their biological activity is determined.