Medium chain triglycerides improve the growth performance, immune and antioxidant functions, and intestinal health of weaned rabbits

Anim Sci J. 2022 Jan-Dec;93(1):e13794. doi: 10.1111/asj.13794.

Abstract

The purpose is to study the effects of different doses of medium chain triglyceride (MCT) on growth performance, immune and oxidative functions, and intestinal health of weaned rabbits. A total of 600 weaned rabbits weighing about 993.26 g and at 35 d of age were randomly divided into five groups. The control group was fed a basal diet containing 2400 mg/kg soybean oil, and the experimental group was substituted with 600, 1200, 1800, and 2400 mg/kg MCT. The whole trial period lasted for 48 d. The results showed that treatment with 2400 mg/kg MCT significantly increased the weaning survival rate and crude fat digestibility (p < 0.05) and dramatically raised the levels of serum immunoglobulin (Ig)A, IgG, IgM, catalase, superoxide dismutase, and total antioxidant capability (p < 0.05). The villus height and crypt depth in 1800 mg/kg MCT group were observably enhanced (p < 0.05). The abundance of Bacteroidetes was significantly increased in 1800 and 2400 mg/kg MCT groups (p < 0.05). In conclusion, 1800 and 2400 mg/kg MCT substituting soybean oil in the diet of weaned rabbits can improve the growth performance and intestinal barrier function of weaned rabbits.

Keywords: digestibility; intestinal health; medium chain triglycerides; performance; weaned rabbits.

Publication types

  • Randomized Controlled Trial, Veterinary

MeSH terms

  • Animals
  • Antioxidants*
  • Dietary Supplements
  • Intestines
  • Rabbits
  • Soybean Oil*
  • Triglycerides
  • Weaning

Substances

  • Antioxidants
  • Soybean Oil
  • Triglycerides