Exosomes as biomarkers and therapeutic measures for ischemic stroke

Eur J Pharmacol. 2023 Jan 15:939:175477. doi: 10.1016/j.ejphar.2022.175477. Epub 2022 Dec 18.

Abstract

Ischemic stroke (IS) is the leading cause of long-term disability in the world and characterized by high morbidity, recurrence, complications, and mortality. Due to the lack of early diagnostic indicators, limited therapeutic measures and inadequate prognostic indicators, the diagnosis and treatment of IS remains a particular challenge at present. It has recently been reported that exosomes (EXOs) play a significant role in the pathogenesis and treatment of IS. The purpose of this paper is to probe the role of EXOs in diagnostic biomarkers and therapeutic measures for IS and to provide innovative ideas for improving the prognosis of IS.

Keywords: Biomarkers; Exosomes; Ischemic stroke; Therapeutic measures.

Publication types

  • Review

MeSH terms

  • Biomarkers
  • Exosomes*
  • Humans
  • Ischemic Stroke*
  • Prognosis
  • Stroke* / diagnosis
  • Stroke* / therapy

Substances

  • Biomarkers