Morphological, biochemical, and transcriptomic characterization of iPSC-derived human RPE cells from normal and Smith-Lemli-Opitz syndrome patients

Mol Vis. 2022 Nov 12:28:394-411. eCollection 2022.

Authors

Michael H Farkas^{1

2

3}, Lara A Skelton^{1

2

3}, Sriganesh Ramachandra-Rao^{1

2

3}, Elizabeth Au¹, Steven J Fliesler^{1

2

3}

Affiliations

¹ Department of Ophthalmology (Ross Eye Institute), The State University of New York- University at Buffalo, Buffalo, NY.
² Department of Biochemistry and the Neuroscience Graduate Program, The State University of New York- University at Buffalo, Buffalo, NY.
³ Research Service, VA Western New York Healthcare System, Buffalo, NY.

PMID: 36540063
PMCID: PMC9744241

No abstract available

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Cholesterol
Gene Expression Profiling
Humans
Induced Pluripotent Stem Cells*
Smith-Lemli-Opitz Syndrome* / genetics
Transcriptome / genetics

Substances

Cholesterol

Grants and funding