Trichloroacetic Acid With Microneedling Versus Trichloroacetic Acid Alone for Treating Melasma

Abstract

Background: Melasma is a common acquired disorder of hyperpigmentation which is difficult to treat.

Objective: We aim to evaluate the efficacy and safety of combined microneedling with trichloroacetic acid in the treatment of melasma.

Patients and methods: Forty women with facial melasma were included and randomly classified into 2 groups. Group A included 20 patients treated with bimonthly session of trichloroacetic acid 25% peeling (8 sessions) combined with a monthly session of microneedling (4 sessions). Group B included the other 20 patients that were treated by bimonthly trichloroacetic acid 25% peeling session (8 sessions) alone.

Results: After 1 and 3 months of treatment, the mean melasma area and severity index, modified melasma area and severity index, and melasma severity index scores showed significant improvement in each group (p < .05 for each). At 1 and 3 months, the mean percentages of change of all scores were significantly higher in group A than group B (p < .05).

Conclusion: Combined trichloroacetic acid peel with microneedling is effective and a safe option for treating melasma.