Percutaneous transcatheter super-selective renal arterial embolization with N-butyl cyanoacrylate for iatrogenic renal hemorrhage

Xishan Li; Guodong Chen; Dongliang Zhu

doi:10.1016/j.jimed.2022.03.008

Percutaneous transcatheter super-selective renal arterial embolization with N-butyl cyanoacrylate for iatrogenic renal hemorrhage

J Interv Med. 2022 Mar 12;5(4):200-206. doi: 10.1016/j.jimed.2022.03.008. eCollection 2022 Nov.

Authors

Xishan Li¹, Guodong Chen¹, Dongliang Zhu²

Affiliations

¹ Department of Interventional Radiology, Guangzhou First People's Hospital, No.1 Panfu Road, Guangzhou, 510180, PR China.
² Department of Interventional Operation Center, Guangzhou First People's Hospital, No.1 Panfu Road, Guangzhou, 510180, PR China.

Abstract

Background: To evaluate the safety and efficacy of percutaneous transcatheter super-selective renal arterial embolization (SRAE) with N-butyl cyanoacrylate (NBCA) for iatrogenic renal hemorrhage.

Methods: Between January 2014 and December 2019, 45 patients (including 18 patients with coagulopathy), who underwent percutaneous transcatheter SRAE with NBCA for iatrogenic renal hemorrhage at our institution, were retrospectively reviewed. The technical success rate, clinical success rate, and embolization-related complications were analyzed. The values of estimated glomerular filtration rate (eGFR), serum creatinine (sCr), and serum urea (sUr) were analyzed at the time of pre-SRAE, post-SRAE, and last follow-up to evaluate the effects of NBCA-based SRAE on renal function.

Results: Diagnostic renal arteriography revealed contrast extravasation in 18 patients and pseudoaneurysms in 27 patients. NBCA mixed with iodized oil in a 1:2-1:4 ratio was the sole embolic agent. No procedure-related mortality or major complications occurred. The technical and clinical success rates were both 100%. The values of eGFR, sCr and sUr were not found to be significantly different between pre-SRAE, post-SRAE and last follow-up (eGFR: 91.52 ± 21.17 vs. 90.98 ± 22.11 vs. 92.14 ± 23.51 mL/min/1.73 m², p = 0.729; sCr: 74.73 ± 11.08 vs. 75.27 ± 12.43 vs. 73.95 ± 10.14 μmol/L, p = 0.543; sUr: 5.69 ± 0.84 vs. 5.71 ± 0.96 vs. 5.70 ± 0.79, p = 0.515, respectively).

Conclusions: Percutaneous transcatheter SRAE with NBCA is a safe and effective treatment modality for iatrogenic renal hemorrhage with no deterioration of renal function.

Keywords: Iatrogenic; N-butyl cyanoacrylate; Renal arterial embolization; Renal hemorrhage; Super-selective.