Human exposure to bisphenol A (BPA) through medical-hospital devices: A systematic review

Environ Toxicol Pharmacol. 2023 Jan:97:104040. doi: 10.1016/j.etap.2022.104040. Epub 2022 Dec 15.

Abstract

This systematic review explored the literature pertaining to patient exposure to bisphenol A (BPA) through medical-hospital devices. The acronym PICO: Patient (Medical-hospital devices), Intervention/Exposure (Bisphenol A), Comparison (Different grades of exposure) and Outcome (Assessment of exposure levels) was used. The databases used were LILACS, IBECS, MEDLINE, Capes Journal Portal, Food Science Source, FSTA and CINAHL with Full Text from EBSCO, Embase and Scopus by Elsevier, Web of Science and SCIELO. A total of 9747 references were found. After removing duplicate records, 7129 studies remained. After applying exclusion criteria and qualitative analysis, 12 articles remained. Studies have shown associations between the use of medical-hospital devices and patients' exposure to BPA. For chronic renal patients, there was an association between plasma BPA and disease severity. This review identifies that exposure to BPA is increased after the use of medical-hospital devices. More studies that address the clinical outcome of patients exposed to medical-hospital materials containing BPA are needed.

Keywords: Bisphenol A (BPA); Endocrine-disrupting chemicals; Medical-hospital devices; Systematic review.

Publication types

  • Systematic Review

MeSH terms

  • Benzhydryl Compounds / analysis
  • Endocrine Disruptors*
  • Hospitals
  • Humans
  • Phenols / analysis

Substances

  • bisphenol A
  • Endocrine Disruptors
  • Phenols
  • Benzhydryl Compounds