Extended-Spectrum β-Lactamase-Producing Escherichia coli in Neonates and Listeria monocytogenes in Young Children with Bacterial Meningitis in Japan

J Pediatric Infect Dis Soc. 2023 Apr 18;12(3):165-168. doi: 10.1093/jpids/piac135.

Abstract

Nationwide surveillance of pediatric bacterial meningitis in Japan from 2019 to 2021 revealed two uncommon situations not covered by the recommended empiric treatment that were not rare in Japan, namely, extended-spectrum β-lactamase-producing-producing Escherichia coli in neonates and Listeria monocytogenes in children older than 1 month.

Keywords: Listeria monocytogenes; ESBL-producing Escherichia coli; bacterial meningitis; empiric treatment; guideline.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Child, Preschool
  • Escherichia coli
  • Escherichia coli Infections* / microbiology
  • Humans
  • Infant
  • Infant, Newborn
  • Japan / epidemiology
  • Listeria monocytogenes*
  • Meningitis, Bacterial* / drug therapy
  • beta-Lactamases

Substances

  • beta-Lactamases
  • Anti-Bacterial Agents