Since there are currently no interesting treatment options for men with early-stage Dupuytren's disease, new, safe and effective treatment methods are required to improve the quality of life of such patients. Over the past decade, isotonic sugar water injections have received increasing attention from clinicians worldwide. Glucopuncture is a new term to describe isotonic sugar water injections into dermis, fascia, muscles, tendons and ligaments. In this clinical case, a 75-year-old man was treated with glucopuncture for a painless nodule on the right hand. A marked reduction in hardness and size of the nodule was observed after six sessions. Establishing a case series with imaging before and after treatment could be a first step to further illustrate the effects of this novel injection technique. Next, randomized controlled trials (RCTs) with sufficient sample size are needed to establish the value of glucopuncture for painless nodules in Dupuytren's disease.
Keywords: case report; dextrose prolotherapy; dupuytren's disease; fibromatosis; glucopuncture; growth factors; isotonic sugar water; local injection; painless nodule; palmar fascia.
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