A case of thoracic SMARCA4-Deficient undifferentiated tumor successfully treated with combination Ipilimumab-Nivolumab

Yoshio Nakano; Daisuke Sekinada; Yusuke Kuze; Norio Okamoto; Iwao Gohma; Yumiko Yasuhara

doi:10.1002/ccr3.6745

A case of thoracic SMARCA4-Deficient undifferentiated tumor successfully treated with combination Ipilimumab-Nivolumab

Clin Case Rep. 2022 Dec 13;10(12):e6745. doi: 10.1002/ccr3.6745. eCollection 2022 Dec.

Authors

Yoshio Nakano¹, Daisuke Sekinada¹, Yusuke Kuze¹, Norio Okamoto¹, Iwao Gohma¹, Yumiko Yasuhara²

Affiliations

¹ Department of Respiratory Medicine Sakai City Medical Center Sakai City Japan.
² Department of Pathology Sakai City Medical Center Sakai City Japan.

Abstract

Thoracic SMARCA4-deficient undifferentiated tumors are rare, with poor prognosis. A 73-year-old man presented to our hospital with dyspnea. Computed tomography-guided biopsy revealed a SMARCA4-deficient undifferentiated tumor. The patient was treated with combination ipilimumab-nivolumab. The tumor reduced in size after two courses.

Keywords: SMARCA4; case report; undifferentiated tumors.

Publication types

Case Reports