Late-onset and congenital hearing loss detected using AABR due to congenital cytomegalovirus infection that improved with valganciclovir

Congenit Anom (Kyoto). 2023 Mar;63(2):40-43. doi: 10.1111/cga.12501. Epub 2022 Dec 25.

Abstract

Congenital cytomegalovirus (cCMV) infection is the most common congenital viral infection and is the leading non-genetic cause of sensorineural hearing loss and an important cause of neurodevelopmental disabilities. Auto auditory brainstem response (AABR) is a simple hearing test and used for the purpose of neonatal hearing screening, but can use it for early detection hard of hearing within the study age of the model. We experienced two case of asymptomatic CMV infection in which congenital and late-onset hearing loss were diagnosed early with AABR, and hearing loss improved with valganciclovir.

Keywords: automated ABR; congenital cytomegalovirus infection; congenital hearing loss; hearing improvement; late-onset hearing loss.

Publication types

  • Case Reports

MeSH terms

  • Cytomegalovirus Infections* / congenital
  • Cytomegalovirus Infections* / diagnosis
  • Evoked Potentials, Auditory, Brain Stem
  • Hearing Loss, Sensorineural* / congenital
  • Hearing Loss, Sensorineural* / diagnosis
  • Humans
  • Infant, Newborn
  • Neonatal Screening / adverse effects
  • Valganciclovir

Substances

  • Valganciclovir