To deal with divergences of functional integrals in field-theoretic simulations (FTS) of complex fluids, the microscopic density is often smeared by being replaced by a convoluted one, typically using a Gaussian masking function. The smearing changes radically the nature of nonbonded interactions of the original microscopic density and results in a regularized model that is free of ultraviolet (UV) divergences. In this work, we first resolve a few fundamental issues related with the use of masking functions for δ-interactions in FTS and then we detail a new methodology that builds on the concept of multiconvoluted inverse potentials and a principle of model equivalence for statistical weights to accommodate more physically relevant interactions in FTS. The capabilities of the new approach are highlighted by examining the Gaussian-regularized Edwards model (GREM) and the Yukawa potential. A successful test calculation of the excess chemical potential of a polymer chain in a good solvent with the GREM illustrates the power of the new theoretical framework.