Rare cause of a resistant hypertension in a middle-aged man: A case report

Clin Case Rep. 2022 Dec 8;10(12):e6606. doi: 10.1002/ccr3.6606. eCollection 2022 Dec.

Abstract

Congenital adrenal hyperplasia associated to 11-beta-hydroxylase deficiency is a rare cause of secondary hypertension, usually discovered during childhood; however, a late diagnosis in adults has also been reported. Despite low cortisol levels, accumulated adrenal steroid precursors can activate the glucocorticoid receptor and thus protect the patient against adrenal crisis.

Keywords: 11‐b‐hydroxylase deficiency; congenital adrenal hyperplasia; secondary hypertension; testicular adrenal rest tumors.

Publication types

  • Case Reports