The greatest unsolved mystery of all is what consciousness is. Torday and Miller have hypothesized that consciousness is the homologous 'equivalent' of our physiology, behaving as our history, providing an algorithm by which evolution can determine how and why to adapt to ever-changing environmental conditions. Complicated physiology was reduced iteratively to the unicell by tracing the cell-cell signaling mechanisms that dealt with emergent threats based on Bayesian statistics. Unlike Darwinian random mutations, the current approach is predicated on structural and functional changes within the context of pre-existing physiologic traits. The cytoskeleton of the cell is a complete representation for all of the phases of life, past, present and future, controlling the Target of Rapamycin gene, which determines all of the stages of life-homeostasis, meiosis and mitosis. Viewed from this perspective, the cell remains at equipoise relative to the Singularity that existed before the Big Bang. The purpose of life is to collect epigenetic marks by pursuing energy flows, not conventional material change due to random mutations. The cytoskeleton universally controls all of the states of the cell - homeostasis, meiosis and mitosis, rendering the status of the cell relative to the prevailing circumstances. Indeed, the cytoskeleton of the cell is a central player in all of the phases of life, past, present and future. The above-described integration of physiology as the cipher for consciousness is quite ingenious as a 'top-down/bottom-up/middle-out' way of ensuring the holism of life and non-life. Recognition of the centrality of the cell has led to a number of novel insights into biology that have been represented by dogma up until now. Consequently, biology has been simplified by shifting from description to mechanism. Based on Ockam's Razor, the cellular approach to evolution is superior to Darwin.
Keywords: Consciousness; Cytoskeleton; Homeostasis; Integration; Physiology.
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