Alternative strategies for Chlamydia treatment: Promising non-antibiotic approaches

Chen Hou; Yingqi Jin; Hua Wu; Pengyi Li; Longyun Liu; Kang Zheng; Chuan Wang

doi:10.3389/fmicb.2022.987662

Alternative strategies for Chlamydia treatment: Promising non-antibiotic approaches

Front Microbiol. 2022 Nov 23:13:987662. doi: 10.3389/fmicb.2022.987662. eCollection 2022.

Authors

Chen Hou¹, Yingqi Jin¹, Hua Wu², Pengyi Li¹, Longyun Liu¹, Kang Zheng², Chuan Wang¹

Affiliations

¹ School of Basic Medicine, Hengyang Medical College, Institute of Pathogenic Biology, University of South China, Hengyang, China.
² Department of Clinical Laboratory, Affiliated Hengyang Hospital of Southern Medical University, Hengyang Central Hospital, Hengyang, China.

Abstract

Chlamydia is an obligate intracellular bacterium where most species are pathogenic and infectious, causing various infectious diseases and complications in humans and animals. Antibiotics are often recommended for the clinical treatment of chlamydial infections. However, extensive research has shown that antibiotics may not be sufficient to eliminate or inhibit infection entirely and have some potential risks, including antibiotic resistance. The impact of chlamydial infection and antibiotic misuse should not be underestimated in public health. This study explores the possibility of new therapeutic techniques, including a review of recent studies on preventing and suppressing chlamydial infection by non-antibiotic compounds.

Keywords: Chlamydia; anti-chlamydial compounds; antibiotic therapy; chlamydial infection; non-antibiotic approaches.

Publication types

Review