Mechanistic Understanding of the Effects of Pectin on In Vivo Starch Digestion: A Review

Nutrients. 2022 Dec 1;14(23):5107. doi: 10.3390/nu14235107.

Abstract

Obesity and type II diabetes are closely related to the rapid digestion of starch. Starch is the major food-energy source for most humans, and thus knowledge about the regulation of starch digestion can contribute to prevention and improved treatment of carbohydrate metabolic disorders such as diabetes. Pectins are plant polysaccharides with complex molecular structures and ubiquitous presence in food, and have diverse effects on starch digestion. Pectins can favorably regulate in vivo starch digestion and blood glucose level responses, and these effects are attributed to several reasons: increasing the viscosity of digesta, inhibiting amylase activity, and regulating some in vivo physiological responses. Pectins can influence starch digestion via multiple mechanisms simultaneously, in ways that are highly structure-dependent. Utilizing the multi-functionalities of pectin could provide more ways to design low glycemic-response food and while avoiding the unpalatable high viscosity in food by which is commonly caused by many other dietary fibers.

Keywords: diabetes; dietary fiber; digestion; glycemic response; pectin; starch.

Publication types

  • Review

MeSH terms

  • Diabetes Mellitus, Type 2*
  • Dietary Fiber / pharmacology
  • Digestion
  • Humans
  • Pectins / pharmacology
  • Starch* / metabolism

Substances

  • Starch
  • Pectins
  • Dietary Fiber