Vitamin K1 and K2 in the Diet of Patients in the Long Term after Kidney Transplantation

Nutrients. 2022 Nov 29;14(23):5070. doi: 10.3390/nu14235070.

Abstract

Vitamin K, especially its K2 form, is considered to be a protective factor against developing vascular changes and bone lesions that are common complications in kidney transplant (KTx) recipients. There is a growing number of studies showing that KTx patients are at risk of vitamin K deficiency. The aim of this study was to evaluate the intake of vitamin K1 and K2 in the diet of patients in the late period after KTx. During a routine visit at one outpatient transplantation clinic in Central Europe, a diet survey questionnaire was filled in by 151 clinically stable KTx recipients and compared with medical history, anthropometric measurements and laboratory tests. Mean vitamin K1 intake was 120.9 ± 49 μg/day and vitamin K2 (MK, menaquinone) intake 28.69 ± 11.36 μg/day, including: MK-4: 25.9 ± 9.9 μg/day; MK-5: 0.1 ± 0.2 μg/day; MK-6: 0.2 ± 0.4 μg/day; MK-7: 0.2 ± 0.23 μg/day; MK-8: 1 ± 1.9 μg/day; MK-9: 0.9 ± 2.3 μg/day; and MK-10: 0.2 ± 0.5 μg/day. Our study showed that KTx recipients' diets contained adequate amounts of vitamin K1, whereas the intake of vitamin K2 seemed insufficient.

Keywords: diet; kidney transplantation; vitamin K.

MeSH terms

  • Diet
  • Humans
  • Kidney Transplantation* / adverse effects
  • Vitamin K
  • Vitamin K 1
  • Vitamin K 2
  • Vitamin K Deficiency*

Substances

  • Vitamin K 1
  • Vitamin K 2
  • Vitamin K

Grants and funding

This research received no external funding.