3D Printing in Regenerative Medicine: Technologies and Resources Utilized

Int J Mol Sci. 2022 Nov 23;23(23):14621. doi: 10.3390/ijms232314621.

Abstract

Over the past ten years, the use of additive manufacturing techniques, also known as "3D printing", has steadily increased in a variety of scientific fields. There are a number of inherent advantages to these fabrication methods over conventional manufacturing due to the way that they work, which is based on the layer-by-layer material-deposition principle. These benefits include the accurate attribution of complex, pre-designed shapes, as well as the use of a variety of innovative raw materials. Its main advantage is the ability to fabricate custom shapes with an interior lattice network connecting them and a porous surface that traditional manufacturing techniques cannot adequately attribute. Such structures are being used for direct implantation into the human body in the biomedical field in areas such as bio-printing, where this potential is being heavily utilized. The fabricated items must be made of biomaterials with the proper mechanical properties, as well as biomaterials that exhibit characteristics such as biocompatibility, bioresorbability, and biodegradability, in order to meet the strict requirements that such procedures impose. The most significant biomaterials used in these techniques are listed in this work, but their advantages and disadvantages are also discussed in relation to the aforementioned properties that are crucial to their use.

Keywords: 3D printing; bio-printing; biomaterials; direct ink writing (DIW); fused deposition modeling (FDM); laser-guided direct writing (LGDW); stereolithography (SLA).

Publication types

  • Review

MeSH terms

  • Biocompatible Materials / chemistry
  • Humans
  • Porosity
  • Printing, Three-Dimensional*
  • Regenerative Medicine*

Substances

  • Biocompatible Materials

Grants and funding

This research received no external funding.