Bioresorbable polylactic acid (PLA) and bioactive glasses (BG) composite: Influence of gold coated of BG powder on mechanical properties and chemical reactivity

J Mech Behav Biomed Mater. 2023 Feb:138:105571. doi: 10.1016/j.jmbbm.2022.105571. Epub 2022 Nov 19.

Abstract

Due to the ageing of the population, the synthesis of biomaterials and the optimization of their physico-chemical characteristics are at the heart of many research projects in regenerative medicine. The emergence of 3D printing techniques has rapidly led to the manufacture PLA-BG composite scaffolds using the FFF (Fused Filament Fabrication) technique. However, this composite presents some problems including a lower mechanical strength than the two compounds alone, probably due to the ionic salting-out induced by the BG. This study aims to counter this phenomenon by coating the BG particles with a thin layer of gold. The 3D composite objects will then be characterized mechanically and biologically to ensure that the bioactive character of the composite is preserved.

Keywords: Bioactive glass; Bioactivity; Bone tissue engineering; Composite materials; Degradable polymers; Mechanical properties; Polylactic acid; Polymer-ceramic composite.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorbable Implants*
  • Polyesters
  • Powders
  • Tissue Scaffolds* / chemistry

Substances

  • poly(lactide)
  • Powders
  • Polyesters