[A particular presentation of a T cell large granular lymphocytic leukaemia]

Abstract

T cell prolymphocytic leukemia (T-PLL) is a rare, aggressive neoplasm derived from post-thymic T cells. Patients are typically middle-aged with a slight male predominance who present with a high white blood cell count, hepatosplenomegaly, lymphadenopathy, and other symptoms typically associated with leukemia. Although cutaneous involvement has been reported in up to 30% of cases of T-PLL, to our knowledge, none have presented with a presentation resembling livedoid vasculopathy. In the correct clinical context, an underlying hematolymphoid neoplasm should be included in the differential diagnosis of a patient presenting with livedoid vasculopathy.

Keywords: Cutaneous lymphomas; LGLL-T; Large granular lymphocyte leukaemia; Leucémie; Leucémie à grands lymphocytes granuleux; Leukemia; Lymphome T; Lymphome cutané; Lymphome intravasculaire; STAT3; STAT5b.