I-LIFT (image-based laser-induced forward transfer) platform for manipulating encoded microparticles

Sumin Lee; Wooseok Lee; Amos Chungwon Lee; Juhong Nam; JinYoung Lee; Hamin Kim; Yunjin Jeong; Huiran Yeom; Namphil Kim; Seo Woo Song; Sunghoon Kwon

doi:10.1063/5.0131733

I-LIFT (image-based laser-induced forward transfer) platform for manipulating encoded microparticles

Biomicrofluidics. 2022 Dec 5;16(6):061101. doi: 10.1063/5.0131733. eCollection 2022 Dec.

Authors

Affiliations

¹ Department of Electrical and Computer Engineering, Seoul National University, Seoul 08826, Republic of Korea.
² Bio-MAX Institute, Seoul National University, Seoul 08826, Republic of Korea.
³ Division of Engineering Science, University of Toronto, Toronto, Ontario M5S 3H6, Canada.
⁴ Interdisciplinary Program in Bioengineering, Seoul National University, Seoul 08826, Republic of Korea.

Abstract

Encoded microparticles have great potential in small-volume multiplexed assays. It is important to link the micro-level assays to the macro-level by indexing and manipulating the microparticles to enhance their versatility. There are technologies to actively manipulate the encoded microparticles, but none is capable of directly manipulating the encoded microparticles with homogeneous physical properties. Here, we report the image-based laser-induced forward transfer system for active manipulation of the graphically encoded microparticles. By demonstrating the direct retrieval of the microparticles of interest, we show that this system has the potential to expand the usage of encoded microparticles.