Robust classification of heart valve sound based on adaptive EMD and feature fusion

PLoS One. 2022 Dec 8;17(12):e0276264. doi: 10.1371/journal.pone.0276264. eCollection 2022.

Abstract

Cardiovascular disease (CVD) is considered one of the leading causes of death worldwide. In recent years, this research area has attracted researchers' attention to investigate heart sounds to diagnose the disease. To effectively distinguish heart valve defects from normal heart sounds, adaptive empirical mode decomposition (EMD) and feature fusion techniques were used to analyze the classification of heart sounds. Based on the correlation coefficient and Root Mean Square Error (RMSE) method, adaptive EMD was proposed under the condition of screening the intrinsic mode function (IMF) components. Adaptive thresholds based on Hausdorff Distance were used to choose the IMF components used for reconstruction. The multidimensional features extracted from the reconstructed signal were ranked and selected. The features of waveform transformation, energy and heart sound signal can indicate the state of heart activity corresponding to various heart sounds. Here, a set of ordinary features were extracted from the time, frequency and nonlinear domains. To extract more compelling features and achieve better classification results, another four cardiac reserve time features were fused. The fusion features were sorted using six different feature selection algorithms. Three classifiers, random forest, decision tree, and K-nearest neighbor, were trained on open source and our databases. Compared to the previous work, our extensive experimental evaluations show that the proposed method can achieve the best results and have the highest accuracy of 99.3% (1.9% improvement in classification accuracy). The excellent results verified the robustness and effectiveness of the fusion features and proposed method.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Heart Sounds*
  • Heart Valves

Grants and funding

This work is supported by the National Natural Science Foundation of China (No. 61901393 and 61571371). There was no additional external funding received for this study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.