Chemical Stability of Petrichorins

Chunshun Li; Ariel M Sarotti; Antonio Hernández Daranas; Xiaohua Wu; Shao-Liang Zheng; Joshua A V Blodgett; Shugeng Cao

doi:10.1021/acs.joc.2c01275

Chemical Stability of Petrichorins

J Org Chem. 2022 Dec 16;87(24):16847-16850. doi: 10.1021/acs.joc.2c01275. Epub 2022 Dec 7.

Authors

Chunshun Li^{1

2}, Ariel M Sarotti³, Antonio Hernández Daranas⁴, Xiaohua Wu¹, Shao-Liang Zheng⁵, Joshua A V Blodgett⁶, Shugeng Cao^{1

2}

Affiliations

¹ Department of Pharmaceutical Sciences, Daniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, 200 West Kawili Street, Hilo, Hawaii 96720, United States.
² Cancer Biology Program, University of Hawaii Cancer Center, 701 Ilalo Street, Honolulu, Hawaii 96813, United States.
³ Instituto de Química Rosario (CONICET), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario 2000, Argentina.
⁴ Instituto de Productos Naturales y Agrobiología, Consejo Superior de Investigaciones Científicas (IPNA-CSIC), 38206 La Laguna, Tenerife, Spain.
⁵ Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States.
⁶ Department of Biology, Washington University in St. Louis, One Brookings Drive, St. Louis, Missouri 63130, United States.

PMID: 36475686
DOI: 10.1021/acs.joc.2c01275

Abstract

The structure of petrichorin C1 (4) converted from petrichorin C (3) was determined using NMR spectroscopy and X-ray crystallography. The chemical stability of petrichorins A and C (1 and 3) was investigated by NMR spectroscopy, X-ray crystallography, and calculations.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Crystallography, X-Ray
Magnetic Resonance Spectroscopy / methods
Models, Molecular*