Role of Uric Acid Levels in the Development of Gestational Diabetes Mellitus: A Review

Cureus. 2022 Nov 3;14(11):e31057. doi: 10.7759/cureus.31057. eCollection 2022 Nov.

Abstract

Gestational diabetes mellitus (GDM) is a common disorder affecting pregnancy. Besides conventional risk factors, several novel risk factors have been linked to causing GDM. Increased serum uric acid levels, also termed hyperuricemia, are regarded as one of the significant risk factors for increased insulin resistance and GDM, causing detrimental impacts on both mother and child. The likelihood of developing GDM is at its peak during the first three months of pregnancy in patients with hyperuricemia. Still, its pathophysiology needs to be evaluated in detail. This review is aimed at assessing the function of hyperuricemia in the development of GDM.

Keywords: elevated uric acid levels; gestational diabetes mellitus; hyperuricemia; predisposing factors; risk factors; serum uric acid.

Publication types

  • Review