Lymphatic malformations in children: retrospective review of surgical and interventional management

Pediatr Surg Int. 2022 Dec 5;39(1):36. doi: 10.1007/s00383-022-05320-x.

Abstract

Purpose: Lymphatic malformations (LMs) are classified as macrocystic, microcystic or mixed. Treatment depends on their characteristics: surgery, sclerotherapy, both combined, systemic treatment or observation. This study aims to analyze the surgical and interventional management of LMs in children over the last two decades in our university hospital.

Methods: Management of children born with LMs between 2000 and 2019 was reviewed. Parameters collected were: malformation characteristics, type of treatment, symptoms, imaging, timing of diagnosis and first treatment, number of interventions, recovery rate, complications and length of stay.

Results: Files of 48 children were reviewed: 27 with macrocystic and 21 with microcystic LMs. There was no statistically significant difference in type of treatment except for combined treatment, more performed in microcystic LMs (p = 0.04). Symptoms, imaging, timing of diagnosis and first treatment, number of interventions and complications were not statistically significant. Overall, the number of surgeries was lower than sclerotherapies (p = 0.04). Recovery rate after surgery was higher in macrocystic LMs (p = 0.01). Complications and length of stay were not statistically significant.

Conclusion: A good rate of recovery was observed when surgery was performed, with no significant increase in complications and length of stay. A prospective study will be determinant to create a decisional algorithm for children with LMs.

Keywords: Lymphatic malformation; Pediatrics; Sclerotherapy; Surgery.

MeSH terms

  • Child
  • Cysts*
  • Humans
  • Infant
  • Lymphatic Abnormalities* / diagnosis
  • Lymphatic Abnormalities* / surgery
  • Prospective Studies
  • Retrospective Studies
  • Sclerotherapy / methods
  • Treatment Outcome